Burkitt's lymphoma in AIDS: cytogenetic study
نویسندگان
چکیده
منابع مشابه
Burkitt's lymphoma in AIDS: cytogenetic study.
Cytogenetic studies were done in two cases of Burkitt's lymphoma in homosexual individuals with possible acquired immune deficiency syndrome (AIDS). The chromosomal abnormalities found are consistent with those previously described in the nonendemic form of Burkitt's lymphoma, with one of the two patients having the variant translocation, t(8;22). The production of the kappa light chain immunog...
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Secondary chromosomal aberrations were surveyed in non-Hodgkin's lymphomas (NHL) reported in the literature with one of the following, presently recognized, primary abnormalities: t(2;5), +3, t(3;14), del(6q), +X, and -Y. Of 2,175 NHLs with clonal karyotypic changes, 908 (42%) had one of the 13 selected primary chromosome rearrangements, and 670 (74%) of these lymphomas displayed additional abn...
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Although a number of studies have indicated correlations between histologic subtypes of tumors and certain nonrandom chromosome changes, cytogenetic studies of lymphoma are in an early stage compared to those of leukemia. No comprehensive analysis of available data has so far been attempted in the literature either. Here we present an analysis of chromosome changes and their correlation with su...
متن کاملCytogenetic studies in non-African Burkitt lymphoma.
A particular translocation between chromosomes 8 and 14 has been found repeatedly in cytogenetic studies of Burkitt lymphoma, both of African and non-African origin. We report here our findings in cytogenetic studies of direct tumor preparations from 18 non-African Burkitt lymphoma patients, 9 of whom also had cell lines available for study. A t(8;14) was found in direct tumor material in 10 of...
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disease, and in other lymphomas. Patients with leukemia and lymphoma, but not carcinomas, also reacted with extracts of tumor-derived lymphoid cell lines. Studies of in vitro cell-mediated cytotoxicity against autologous tumor cells, using the 51Cr release assay, also gave evidence for reactivity against tumor-associated antigens. In humoral and cell-mediated cytotoxicity assays against lymphoi...
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ژورنال
عنوان ژورنال: Blood
سال: 1984
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v63.4.818.818